Organoid-derived human retinal progenitor cells promote early dedifferentiation of Müller glia in Royal College of Surgeons rats

AIM: To explore whether the subretinal transplantation of retinal progenitor cells from human embryonic stem cell-derived retinal organoid (hERO-RPCs) could promote Müller glia dedifferentiation and transdifferentiation, thus improving visual function and delaying retinal degenerative progression. M...

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Bibliographic Details
Main Authors: Qiang Guo, Yu-Xiao Zeng, Shu-Dong Huang, Ting Zou, Zheng-Qin Yin
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2023-04-01
Series:International Journal of Ophthalmology
Subjects:
Online Access:http://ies.ijo.cn/en_publish/2023/4/20230401.pdf