The Phenotype of Mesenchymal Stromal Cell and Articular Chondrocyte Cocultures on Highly Porous Bilayer Poly-L-Lactic Acid Scaffolds Produced by Thermally Induced Phase Separation and Supplemented with Hydroxyapatite

The Phenotype of Mesenchymal Stromal Cell and Articular Chondrocyte Cocultures on Highly Porous Bilayer Poly-L-Lactic Acid Scaffolds Produced by Thermally Induced Phase Separation and Supplemented with Hydroxyapatite

Bilayer scaffolds could provide a suitable topology for osteochondral defect repair mimicking cartilage and subchondral bone architecture. Hence, they could facilitate the chondro- and osteogenic lineage commitment of multipotent mesenchymal stromal cells (MSCs) with hydroxyapatite, the major inorga...

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Bibliographic Details
Main Authors: Wally Ferraro, Aurelio Civilleri, Clemens Gögele, Camilla Carbone, Ilenia Vitrano, Francesco Carfi Pavia, Valerio Brucato, Vincenzo La Carrubba, Christian Werner, Kerstin Schäfer-Eckart, Gundula Schulze-Tanzil
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Polymers
Subjects:
tissue engineering
hydroxyapatite
poly-L-lactic acid
mesenchymal stromal cells
chondrocytes
osteogenesis
Online Access:https://www.mdpi.com/2073-4360/16/3/331

Internet

https://www.mdpi.com/2073-4360/16/3/331

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