Cartilage regeneration using improved surface electrospun bilayer polycaprolactone scaffolds loaded with transforming growth factor-beta 3 and rabbit muscle-derived stem cells

Cartilage regeneration using improved surface electrospun bilayer polycaprolactone scaffolds loaded with transforming growth factor-beta 3 and rabbit muscle-derived stem cells

Polycaprolactone (PCL) has recently received significant attention due to its mechanical strength, low immunogenicity, elasticity, and biodegradability. Therefore, it is perfectly suitable for cartilage tissue engineering. PCL is relatively hydrophobic in nature, so its hydrophilicity needs to be en...

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Bibliographic Details
Main Authors: Mantas Malinauskas, Lina Jankauskaite, Lauryna Aukstikalne, Lauryna Dabasinskaite, Augustinas Rimkunas, Tomas Mickevicius, Alius Pockevicius, Edvinas Krugly, Dainius Martuzevicius, Darius Ciuzas, Odeta Baniukaitiene, Arvydas Usas
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
cartilage regeneration
PCL scaffolds
ozone treatment
transforming growth factor-beta 3
rabbit MDSCs
cell-scaffold construct
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.971294/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2022.971294/full

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