In Vitro Performance of an Investigational Vibrating-Membrane Nebulizer with Surfactant under Simulated, Non-Invasive Neonatal Ventilation Conditions: Influence of Continuous Positive Airway Pressure Interface and Nebulizer Positioning on the Lung Dose

In Vitro Performance of an Investigational Vibrating-Membrane Nebulizer with Surfactant under Simulated, Non-Invasive Neonatal Ventilation Conditions: Influence of Continuous Positive Airway Pressure Interface and Nebulizer Positioning on the Lung Dose

Non-invasive delivery of nebulized surfactant has been a long-pursued goal in neonatology. Our aim was to evaluate the performance of an investigational vibrating-membrane nebulizer in a realistic non-invasive neonatal ventilation circuit with different configurations. Surfactant (aerosols were gene...

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Bibliographic Details
Main Authors: Federico Bianco, Elena Pasini, Marcello Nutini, Xabier Murgia, Carolin Stoeckl, Martin Schlun, Uwe Hetzer, Sauro Bonelli, Marta Lombardini, Ilaria Milesi, Marisa Pertile, Stefan Minocchieri, Fabrizio Salomone, Albert Bucholski
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Pharmaceutics
Subjects:
eflow nebulizer
nebulized surfactant
aerosol
non-invasive ventilation
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Online Access:https://www.mdpi.com/1999-4923/12/3/257

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https://www.mdpi.com/1999-4923/12/3/257

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