PTD4 Peptide Increases Neural Viability in an In Vitro Model of Acute Ischemic Stroke

PTD4 Peptide Increases Neural Viability in an In Vitro Model of Acute Ischemic Stroke

Ischemic stroke is a disturbance in cerebral blood flow caused by brain tissue ischemia and hypoxia. We optimized a multifactorial in vitro model of acute ischemic stroke using rat primary neural cultures. This model was exploited to investigate the pro-viable activity of cell-penetrating peptides:...

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Bibliographic Details
Main Authors: Jarosław Mazuryk, Izabela Puchalska, Kamil Koziński, Magdalena J. Ślusarz, Jarosław Ruczyński, Piotr Rekowski, Piotr Rogujski, Rafał Płatek, Marta Barbara Wiśniewska, Arkadiusz Piotrowski, Łukasz Janus, Piotr M. Skowron, Michał Pikuła, Paweł Sachadyn, Sylwia Rodziewicz-Motowidło, Artur Czupryn, Piotr Mucha
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
arginine-rich peptides
cell-penetrating peptides
excitotoxicity
ischemic stroke
neural viability
neuroprotection
Online Access:https://www.mdpi.com/1422-0067/22/11/6086

Internet

https://www.mdpi.com/1422-0067/22/11/6086

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