Global chromatin mobility induced by a DSB is dictated by chromosomal conformation and defines the HR outcome

Global chromatin mobility induced by a DSB is dictated by chromosomal conformation and defines the HR outcome

Repair of DNA double-strand breaks (DSBs) is crucial for genome integrity. A conserved response to DSBs is an increase in chromatin mobility that can be local, at the site of the DSB, or global, at undamaged regions of the genome. Here, we address the function of global chromatin mobility during hom...

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Bibliographic Details
Main Authors: Fabiola García Fernández, Etienne Almayrac, Ànnia Carré Simon, Renaud Batrin, Yasmine Khalil, Michel Boissac, Emmanuelle Fabre
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-09-01
Series:eLife
Subjects:
chromatin dynamics
chromosome organization
double-strand break
homologous recombination
γ-H2A(X)
yeast
Online Access:https://elifesciences.org/articles/78015

Internet

https://elifesciences.org/articles/78015

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