Guizhi Fuling capsule relieves memory deficits by inhibition of microglial neuroinflammation through blocking JAK2/STAT3 pathway in presenilin1/2 conditional double knockout mice

Guizhi Fuling capsule relieves memory deficits by inhibition of microglial neuroinflammation through blocking JAK2/STAT3 pathway in presenilin1/2 conditional double knockout mice

Chronic neuroinflammation has been regarded as an important part of the pathological initiation of Alzheimer’s disease (AD), which is associated with the regulation of microglial activation. Preventing microglial activation to inhibit neuroinflammation may become a potential target for the treatment...

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Bibliographic Details
Main Authors: Guang Yang, Yuting Tong, Xingyu Wang, Chenyi Zhao, Zongtao Ba, Reaila Ahelijiang, Xinjuan Liu, Waimao Gao, Yan Zhao, Yining Gu, Jianmei Yang, Ying Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Immunology
Subjects:
Guizhi Fuling capsule
Alzheimer’s disease
memory deficits
microglial activation
neuroinflammation
JAK2/STAT3 pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1185570/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1185570/full

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