Pathophysiology of matrix metalloproteinases in breast cancer progression

Pathophysiology of matrix metalloproteinases in breast cancer progression

Matrix metalloproteinases (MMPs) are secretary or membrane type proteolytic enzymes that act on extracellular matrix protein components such as collagens, gelatins, elastins, laminins, fibronectins, and integrins. MMPs are synthesized as zymogens and are activated to functional forms on autoproteoly...

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Bibliographic Details
Main Authors: Sudheer Kumar Katari, Chiranjeevi Pasala, Ravina Madhulitha Nalamolu, Umakanth Naik Vankadoth, Sharon Priya Alexander, Siva Ranjani Pakala, Aparna R Bitla, Amineni Umamaheswari
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Journal of Clinical and Scientific Research
Subjects:
angiogenesis
breast cancer
extracellular matrix
invasion
matrix metalloproteinases
metastasis
Online Access:http://www.jcsr.co.in/article.asp?issn=2277-5706;year=2019;volume=8;issue=3;spage=145;epage=150;aulast=Katari

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http://www.jcsr.co.in/article.asp?issn=2277-5706;year=2019;volume=8;issue=3;spage=145;epage=150;aulast=Katari

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