Titanium particles damage osteocytes and inhibit osteoblast differentiation

Abstract Purposes to study the effect of titanium particles on MLO-Y4 and the effects of osteocytes alterations on osteoblasts. Methods cultured MLO-Y4 osteocytes were exposed to different concentrations of titanium (Ti) particles, cell viability was measured using the Cell Counting Kit-8 (CCK-8) as...

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Bibliographic Details
Main Authors: Li Chen, Ziyue Wang, Wei Xu, Qirong Dong
Format: Article
Language:English
Published: SpringerOpen 2020-07-01
Series:Journal of Experimental Orthopaedics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s40634-020-00268-0