The Effects of Human Milk Oligosaccharides on Gut Microbiota, Metabolite Profiles and Host Mucosal Response in Patients with Irritable Bowel Syndrome

The Effects of Human Milk Oligosaccharides on Gut Microbiota, Metabolite Profiles and Host Mucosal Response in Patients with Irritable Bowel Syndrome

Background: Human milk oligosaccharide supplementation safely modulates fecal bifidobacteria abundance and holds the potential to manage symptoms in irritable bowel syndrome (IBS). Here, we aimed to determine the role of a 4:1 mix of 2′-O-fucosyllactose and lacto-N-neotetraose (2′FL/LNnT) on the mod...

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Bibliographic Details
Main Authors: Cristina Iribarren, Maria K. Magnusson, Louise K. Vigsnæs, Imran Aziz, Ingvild Dybdrodt Amundsen, Tanja Šuligoj, Nathalie Juge, Piyush Patel, Maria Sapnara, Lea Johnsen, Nikolaj Sørensen, Johanna Sundin, Hans Törnblom, Magnus Simrén, Lena Öhman
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Nutrients
Subjects:
2′-O-fucosyllactose
antibacterial response
gut microenvironment
human milk oligosaccharides
irritable bowel syndrome
lacto-N-neotetraose
Online Access:https://www.mdpi.com/2072-6643/13/11/3836

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https://www.mdpi.com/2072-6643/13/11/3836

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