Molecular identity of axonal sodium channels in human cortical pyramidal cells

Studies in rodents revealed that selective accumulation of Na+ channel subtypes at the axon initial segment (AIS) determines action potential (AP) initiation and backpropagation in cortical pyramidal cells (PCs); however, in human cortex, the molecular identity of Na+ channels distributed at PC axon...

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Bibliographic Details
Main Authors: Cuiping eTian, Kaiyan eWang, Wei eKe, Hui eGuo, Yousheng eShu
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-09-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00297/full