Molecular identity of axonal sodium channels in human cortical pyramidal cells

Molecular identity of axonal sodium channels in human cortical pyramidal cells

Studies in rodents revealed that selective accumulation of Na+ channel subtypes at the axon initial segment (AIS) determines action potential (AP) initiation and backpropagation in cortical pyramidal cells (PCs); however, in human cortex, the molecular identity of Na+ channels distributed at PC axon...

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Bibliographic Details
Main Authors: Cuiping eTian, Kaiyan eWang, Wei eKe, Hui eGuo, Yousheng eShu
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-09-01
Series:Frontiers in Cellular Neuroscience
Subjects:
parvalbumin
pyramidal cell
axon initial segment
human cortex
node of Ranvier
chandelier cell
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00297/full

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