Whole-Exome Sequencing Identified Genes Responsible for Thoracic Aortic Aneurysms and Dissections in three Chinese Families

Whole-Exome Sequencing Identified Genes Responsible for Thoracic Aortic Aneurysms and Dissections in three Chinese Families

Thoracic aortic aneurysms and dissections are precarious conditions that often cannot be diagnosed with fatal outcomes. Over the last few years, pathogenic variants in numerous genes have been identified that predispose to heritable presentations of TAAD. An evidence-based strategy for the selection...

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Bibliographic Details
Main Authors: Renle Guo, Pengcheng Du, Yifei Pei, Jin Yang, Shuangshuang Li, Sheng Chang, Huiying Sun, Xiaomin He, Jian Dong, Jian Zhou, Zaiping Jing
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Genetics
Subjects:
thoracic aortic aneurysms and dissections
pathogenesis
familial inheritance
whole-exome sequencing
susceptibility gene
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.910932/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2022.910932/full

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