Sympathetic Denervation Ameliorates Renal Fibrosis via Inhibition of Cellular Senescence

Sympathetic Denervation Ameliorates Renal Fibrosis via Inhibition of Cellular Senescence

ObjectiveContinuous overactivation of the renal sympathetic nerve is considered to be an important cause of renal fibrosis. Accumulated senescent cells in the damaged kidney have metabolic activities and secrete amounts of proinflammatory factors as part of the SASP (the senescence-associated secret...

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Bibliographic Details
Main Authors: Qian Li, Yuanjun Deng, Lele Liu, Chunjiang Zhang, Yang Cai, Tianjing Zhang, Min Han, Gang Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Immunology
Subjects:
sympathetic denervation
cellular senescence
neurometabolic
neuroimmune
renal fibrosis.
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.823935/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.823935/full

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