Ischemic postconditioning and pinacidil suppress calcium overload in anoxia-reoxygenation cardiomyocytes via down-regulation of the calcium-sensing receptor
Ischemic postconditioning (IPC) and ATP sensitive potassium channel (KATP) agonists (e.g. pinacidil and diazoxide) postconditioning are effective methods to defeat myocardial ischemia-reperfusion (I/R) injury, but their specific mechanisms of reducing I/R injury are not fully understood. We observed...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2016-11-01
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Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/2612.pdf |