RETRACTED: Targeting MYCN IRES in MYCN‐amplified neuroblastoma with miR‐375 inhibits tumor growth and sensitizes tumor cells to radiation

RETRACTED: Targeting MYCN IRES in MYCN‐amplified neuroblastoma with miR‐375 inhibits tumor growth and sensitizes tumor cells to radiation

The MYCN oncogene is amplified in 20% of neuroblastomas, leading to its overexpression at both the mRNA and protein levels. MYCN overexpression is strongly associated with advanced disease stage, rapid tumor progression and a worse prognosis. In the present study, we identified microRNA‐375 (miR‐375...

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Bibliographic Details
Main Authors: Hailong Zhang, Tao Liu, Sha Yi, Lubing Gu, Muxiang Zhou
Format: Article
Language:English
Published: Wiley 2015-08-01
Series:Molecular Oncology
Subjects:
miR-375
MYCN
IRES
Neuroblastoma
Ionizing irradiation
Online Access:https://doi.org/10.1016/j.molonc.2015.03.005

Internet

https://doi.org/10.1016/j.molonc.2015.03.005

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