A mannitol-modified emodin nano-drug restores the intestinal barrier function and alleviates inflammation in a mouse model of DSS-induced ulcerative colitis

A mannitol-modified emodin nano-drug restores the intestinal barrier function and alleviates inflammation in a mouse model of DSS-induced ulcerative colitis

Abstract Background Ulcerative colitis (UC) is an inflammatory disease of the colon that is characterized by mucosal ulcers. Given its increasing prevalence worldwide, it is imperative to develop safe and effective drugs for treating UC. Emodin, a natural anthraquinone derivative present in various...

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Bibliographic Details
Main Authors: Yin-Yue Xu, Min Zhu, Jiang Wu, Long-Biao Luo, Si-jing Dong, Meng-Gai Zhang, Xue Liu, Ke Wang, Hua Luo, Wang-Hui Jing, Lin Wang, Si-Cen Wang
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Chinese Medicine
Subjects:
Ulcerative colitis
Emodin
Nano drug delivery system
Intestinal barrier
Online Access:https://doi.org/10.1186/s13020-023-00801-0

Internet

https://doi.org/10.1186/s13020-023-00801-0

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