Chronic treatment with the nitric oxide synthase inhibitor, L-NAME, attenuates estradiol-mediated improvement of learning and memory in ovariectomized rats

Chronic treatment with the nitric oxide synthase inhibitor, L-NAME, attenuates estradiol-mediated improvement of learning and memory in ovariectomized rats

INTRODUCTION: The role of ovarian hormones and nitric oxide in learning and memory has been widely investigated. OBJECTIVE: The present study was carried out to evaluate the effect of the nitric oxide synthase (NOS) inhibitor, N (G)-nitro-L-arginine methyl ester (L-NAME), on the ability of estradiol...

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Bibliographic Details
Main Authors: Hamid Azizi-Malekabadi, Mahmoud Hosseini, Fatima Saffarzadeh, Reza Karami, Fatimeh Khodabandehloo
Format: Article
Language:English
Published: Elsevier España 2011-01-01
Series:Clinics
Subjects:
Estradiol
L-NAME
Morris water maze
Learning
Memory
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322011000400024

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322011000400024

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