Crim1 inhibits angiotensin II-induced hypertrophy and preserves Kv4.2 expression in cardiomyocytes

Crim1 inhibits angiotensin II-induced hypertrophy and preserves Kv4.2 expression in cardiomyocytes

Objective(s): Angiotensin II (Ang II) plays a key role in the regulation of myocardial hypertrophy via downstream cysteine-rich transmembrane bone morphogenetic protein regulator 1 (Crim1). However, it is still unclear whether Crim1 is involved in ionic channel remodeling. The study aimed to explore...

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Bibliographic Details
Main Authors: Jionghong He, Guiling Xia, long yang, Zhi Jiang, Ying Yang, Zhaomei Huo, Chuxian Guo
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2022-10-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
angiotensin ii
cysteine-rich transmembrane
bone morphogenetic protein - regulator 1
ion channel remodeling
transient outward - potassium current
ventricular hypertrophy
Online Access:https://ijbms.mums.ac.ir/article_21061_d38a9b5e856a34a2903acba7802d2288.pdf

Internet

https://ijbms.mums.ac.ir/article_21061_d38a9b5e856a34a2903acba7802d2288.pdf

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