A continuum of zinc finger transcription factor retention on native chromatin underlies dynamic genome organization

A continuum of zinc finger transcription factor retention on native chromatin underlies dynamic genome organization

Abstract Transcription factor (TF) residence on chromatin translates into quantitative transcriptional or structural outcomes on genome. Commonly used formaldehyde crosslinking fixes TF-DNA interactions cumulatively and compromises the measured occupancy level. Here we mapped the occupancy level of...

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Bibliographic Details
Main Authors: Siling Hu, Yangying Liu, Qifan Zhang, Juan Bai, Chenhuan Xu
Format: Article
Language:English
Published: Springer Nature 2024-05-01
Series:Molecular Systems Biology
Subjects:
Native Chromatin
Chromatin Structure
CTCF
Transcription Factor
ChIP
Online Access:https://doi.org/10.1038/s44320-024-00038-5

Internet

https://doi.org/10.1038/s44320-024-00038-5

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