Dexamethasone Impairs ATP Production and Mitochondrial Performance in Human Trabecular Meshwork Cells

Mitochondrial damage occurs in human trabecular meshwork (HTM) cells as a result of normal aging and in open angle glaucoma. Using an HTM cell model, we quantified mitochondrial function and ATP generation rates after dexamethasone (Dex) and TGF-β2 treatments, frequently used as in vitro models of g...

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Bibliographic Details
Main Authors: Shane Kennedy, Clayton Williams, Emily Tsaturian, Joshua T. Morgan
Format: Article
Language:English
Published: MDPI AG 2024-09-01
Series:Current Issues in Molecular Biology
Subjects:
Online Access:https://www.mdpi.com/1467-3045/46/9/587