Make or break: the thermodynamic equilibrium of polyphosphate kinase-catalysed reactions

Polyphosphate kinases (PPKs) have become popular biocatalysts for nucleotide 5'-triphosphate (NTP) synthesis and regeneration. Two unrelated families are described: PPK1 and PPK2. They are structurally unrelated and use different catalytic mechanisms. PPK1 enzymes prefer the usage of adenosine...

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Bibliographic Details
Main Authors: Michael Keppler, Sandra Moser, Henning J. Jessen, Christoph Held, Jennifer N. Andexer
Format: Article
Language:English
Published: Beilstein-Institut 2022-09-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.18.134