The Novel Peptide Chm-273s Has Therapeutic Potential for Metabolic Disorders: Evidence from In Vitro Studies and High-Sucrose Diet and High-Fat Diet Rodent Models

The Novel Peptide Chm-273s Has Therapeutic Potential for Metabolic Disorders: Evidence from In Vitro Studies and High-Sucrose Diet and High-Fat Diet Rodent Models

The aim of this study was to develop a novel peptide potentially applicable for the treatment of metabolic conditions, such as obesity and type 2 diabetes (T2D). We identified CHM-273S from the list of peptides from milk hydrolysate obtained by HPLC/MS-MS. In vitro analysis of primary murine fibrobl...

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Bibliographic Details
Main Authors: Nikita A. Mitkin, Vsevolod V. Pavshintcev, Iuliia A. Sukhanova, Igor I. Doronin, Gennady A. Babkin, Marianna Sadagurski, Anton V. Malyshev
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Pharmaceutics
Subjects:
novel treatment
peptide drugs
insulin signaling
central action
prediabetes
Online Access:https://www.mdpi.com/1999-4923/14/10/2088

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https://www.mdpi.com/1999-4923/14/10/2088

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