The zebrafish paralog six2b is required for early proximal pronephros morphogenesis

Abstract The transcription factor Six2 plays a crucial role in maintaining self-renewing nephron progenitor cap mesenchyme (CM) during metanephric kidney development. In mouse and human, expression at single-cell resolution has detected Six2 in cells as they leave the CM pool and differentiate. The...

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Bibliographic Details
Main Authors: Beau Belcher, Justin Vestal, Samuel Lane, Margaret Kell, Luke Smith, Troy Camarata
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-47046-3