Mutation Hotspots Found in Bladder Cancer Aid Prediction of Carcinogenic Risk in Normal Urothelium

Mutation Hotspots Found in Bladder Cancer Aid Prediction of Carcinogenic Risk in Normal Urothelium

More than 80,000 new cases of bladder cancer are estimated to be diagnosed in 2023. However, the 5-year survival rate for bladder cancer has not changed in decades, highlighting the need for prevention. Numerous cancer-causing mutations are present in the urothelium long before signs of cancer arise...

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Bibliographic Details
Main Authors: Sydney R. Grant, Li Tang, Lei Wei, Barbara A. Foster, Gyorgy Paragh, Wendy J. Huss
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:International Journal of Molecular Sciences
Subjects:
urothelium
mutation hotspot
clonal mutations
carcinogenesis
bladder cancer
machine learning
Online Access:https://www.mdpi.com/1422-0067/24/9/7852

Internet

https://www.mdpi.com/1422-0067/24/9/7852

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