Relative comparison of chronic kidney disease-mineral and bone disorder rat models

Objective: The aim of this study is to establish a suitable animal model of chronic kidney disease–mineral and bone disorder (CKD–MBD) by comparing CKD–MBD rat models induced by 5/6 Nx, AN, and UUO, accompanied by a low-calcium and high-phosphorus diet.Methods: Sprague‒Dawley rats were randomly divi...

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Bibliographic Details
Main Authors: Xiaoqiong Zhang, Ting Li, Lijuan Wang, Yanhui Li, Taoren Ruan, Xiaohong Guo, Qin Wang, Xianli Meng
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2023.1083725/full