Transcriptome profiling of human hepatocytes treated with Aroclor 1254 reveals transcription factor regulatory networks and clusters of regulated genes

<p>Abstract</p> <p>Background</p> <p>Aroclor 1254 is a well-known hepatotoxin and consists of a complex mixture of polychlorinated biphenyls (PCBs), some of which have the ability to activate the aryl hydrocarbon receptor (AhR) and other transcription factors (TFs). Alt...

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Bibliographic Details
Main Authors: Borlak Jürgen, Reymann Susanne
Format: Article
Language:English
Published: BMC 2006-08-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/7/217