Liver-specific Mettl3 ablation delays liver regeneration in mice

This study investigated the role of N6-methyladenosine RNA methylation in liver regeneration following partial hepatectomy in mice. We created a liver-specific knockout mouse model by the deletion of Mettl3, a key component of the N6-methyladenosine methyltransferase complex, using the albumin-Cre s...

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Bibliographic Details
Main Authors: Jiaxiang Meng, Zhicong Zhao, Zhifeng Xi, Qiang Xia
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2022-05-01
Series:Genes and Diseases
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304220301331