Functional Effects In Silico Prediction for Androgen Receptor Ligand-Binding Domain Novel I836S Mutation

Functional Effects In Silico Prediction for Androgen Receptor Ligand-Binding Domain Novel I836S Mutation

Over 1000 mutations are described in the androgen receptor (AR) gene. Of those, about 600 were found in androgen insensitivity syndrome (AIS) patients, among which 400 mutations affect the ligand-binding domain (LBD) of the AR protein. Recently, we reported a novel missense mutation c.2507T>G I83...

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Bibliographic Details
Main Authors: Alexey Rayevsky, Dmytro Sirokha, Dariia Samofalova, Dmytro Lozhko, Olexandra Gorodna, Inga Prokopenko, Liudmyla Livshits
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Life
Subjects:
androgen receptor
ligand-binding domain
mutation
molecular modeling
molecular dynamics
time isolated RMSF
Online Access:https://www.mdpi.com/2075-1729/11/7/659

Internet

https://www.mdpi.com/2075-1729/11/7/659

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