Generation of mesenchyme free intestinal organoids from human induced pluripotent stem cells

Generation of mesenchyme free intestinal organoids from human induced pluripotent stem cells

Human induced pluripotent stem cell-derived intestinal organoids (HIOs) are powerful tools to study development and diseases of the gastrointestinal tract. Here, the authors develop a directed differentiation protocol to generate mesenchyme-free HIOs that can be patterned towards proximal small inte...

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Bibliographic Details
Main Authors: Aditya Mithal, Amalia Capilla, Dar Heinze, Andrew Berical, Carlos Villacorta-Martin, Marall Vedaie, Anjali Jacob, Kristine Abo, Aleksander Szymaniak, Megan Peasley, Alexander Stuffer, John Mahoney, Darrell N. Kotton, Finn Hawkins, Gustavo Mostoslavsky
Format: Article
Language:English
Published: Nature Portfolio 2020-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-13916-6

Internet

https://doi.org/10.1038/s41467-019-13916-6

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