METTL3-Modulated <i>circUHRF2</i> Promotes Colorectal Cancer Stemness and Metastasis through Increasing <i>DDX27</i> mRNA Stability by Recruiting IGF2BP1

METTL3-Modulated <i>circUHRF2</i> Promotes Colorectal Cancer Stemness and Metastasis through Increasing <i>DDX27</i> mRNA Stability by Recruiting IGF2BP1

Increasing evidence has implicated that circular RNAs (circRNAs) exert important roles in colorectal cancer (CRC) occurrence and progression. However, the role of a novel circRNA, <i>circUHRF2</i>, remains unknown in CRC. Our work aimed at identifying the functional roles of <i>cir...

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Bibliographic Details
Main Authors: Miao Chen, Buning Tian, Gui Hu, Yihang Guo
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Cancers
Subjects:
colorectal cancer
stemness
tumor metastasis
<i>circUHRF2</i>
DDX27 signaling
N6-methyladenine (m<sup>6</sup>A) modification
Online Access:https://www.mdpi.com/2072-6694/15/12/3148

Internet

https://www.mdpi.com/2072-6694/15/12/3148

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