Gut microbiota-derived butyrate selectively interferes with growth of carbapenem-resistant Escherichia coli based on their resistance mechanism

Gut microbiota-derived butyrate selectively interferes with growth of carbapenem-resistant Escherichia coli based on their resistance mechanism

We investigated consequences of resistance acquisition in Escherichia coli clinical isolates during anaerobic (continuous culture) growth and examined their sensitivity to butyrate, a hallmark metabolite of healthy gut microbiota. Strains were stratified based on carrying either a carbapenemase (CAR...

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Bibliographic Details
Main Authors: Eva Happ, Kora Schulze, Zinia Afrin, Sabrina Woltemate, Pia Görner, Stefan Ziesing, Dirk Schlüter, Robert Geffers, Volker Winstel, Marius Vital
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Gut Microbes
Subjects:
Antibiotic resistance
butyrate
Escherichia coli
bacterial physiology
anaerobic cultivation
gene expression
Online Access:https://www.tandfonline.com/doi/10.1080/19490976.2024.2397058

Internet

https://www.tandfonline.com/doi/10.1080/19490976.2024.2397058

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