Host defense mechanism-based rational design of live vaccine.

Host defense mechanism-based rational design of live vaccine.

Live attenuated vaccine (LAV), mimicking natural infection, provides an excellent protection against microbial infection. The development of LAV, however, still remains highly empirical and the rational design of clinically useful LAV is scarcely available. Apoptosis and caspase activation are gener...

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Bibliographic Details
Main Authors: Yo Han Jang, Young Ho Byun, Kwang-Hee Lee, Eun-Sook Park, Yun Ha Lee, Yoon-Jae Lee, Jinhee Lee, Kyun-Hwan Kim, Baik Lin Seong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3788757?pdf=render

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http://europepmc.org/articles/PMC3788757?pdf=render

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