Promoter Targeting RNAs: Unexpected Contributors to the Control of HIV-1 Transcription

In spite of prolonged and intensive treatment with combined antiretroviral therapy (cART), which efficiently suppresses plasma viremia, the integrated provirus of HIV-1 persists in resting memory CD4+ T cells as latent infection. Treatment with cART does not substantially reduce the burden of latent...

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Detalhes bibliográficos
Main Authors: Kazuo Suzuki, Chantelle Ahlenstiel, Katherine Marks, Anthony D Kelleher
Formato: Artigo
Idioma:English
Publicado em: Elsevier 2015-01-01
Colecção:Molecular Therapy: Nucleic Acids
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2162253116300063