Local carbachol application induces oral microvascular recruitment and improves gastric tissue oxygenation during hemorrhagic shock in dogs

IntroductionHemorrhagic shock is characterized by derangements of the gastrointestinal microcirculation. Topical therapy with nitroglycerine or iloprost improves gastric tissue oxygenation but not regional perfusion, probably due to precapillary adrenergic innervation. Therefore, this study was desi...

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Bibliographic Details
Main Authors: Stefan Hof, Lara Lingens, Marius Michels, Carsten Marcus, Anne Kuebart, Anna Herminghaus, Inge Bauer, Olaf Picker, Richard Truse, Christian Vollmer
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1369617/full