C-terminal domain small phosphatase-like 2 promotes epithelial-to-mesenchymal transition via Snail dephosphorylation and stabilization

C-terminal domain small phosphatase-like 2 promotes epithelial-to-mesenchymal transition via Snail dephosphorylation and stabilization

The epithelial-to-mesenchymal transition (EMT) is a cellular reprogramming process converting epithelial cells into mesenchymal cell morphology. Snail is a critical regulator of EMT by both suppressing epithelial gene expression and promoting mesenchymal gene expression. Expression and activity of S...

Full description

Bibliographic Details
Main Authors: Yulan Zhao, Jinquan Liu, Fenfang Chen, Xin-Hua Feng
Format: Article
Language:English
Published: The Royal Society 2018-04-01
Series:Open Biology
Subjects:
snail
ctdspl2/scp4
phosphatase
tgf-β signalling
phosphorylation
emt
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.170274

Internet

https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.170274

Similar Items