Molecular and Clinical Features of EGFR-TKI-Associated Lung Injury

Molecular and Clinical Features of EGFR-TKI-Associated Lung Injury

The tyrosine kinase activity of epidermal growth factor receptors (EGFRs) plays critical roles in cell proliferation, regeneration, tumorigenesis, and anticancer resistance. Non-small-cell lung cancer patients who responded to EGFR-tyrosine kinase inhibitors (EGFR-TKIs) and obtained survival benefit...

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Bibliographic Details
Main Authors: Tohru Ohmori, Toshimitsu Yamaoka, Koichi Ando, Sojiro Kusumoto, Yasunari Kishino, Ryou Manabe, Hironori Sagara
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
EGFR-TKIs
lung injury
inflammation
TNF
Online Access:https://www.mdpi.com/1422-0067/22/2/792

Internet

https://www.mdpi.com/1422-0067/22/2/792

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