Patients with Obesity and a History of Metformin Treatment Have Lower Influenza Mortality: A Retrospective Cohort Study

Background: Obesity is a risk factor for the development of influenza by leading to a chronic inflammatory state and T-cell dysfunction. Based upon preclinical research, metformin has influenza activity by restoring T-cell function and improving the immune response. Objective: We aimed to evaluate t...

Full description

Bibliographic Details
Main Authors: Tammy H. Cummings, Joseph Magagnoli, James W. Hardin, S. Scott Sutton
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Pathogens
Subjects:
Online Access:https://www.mdpi.com/2076-0817/11/2/270