Synthesis of new 1,4-disubstituted 1,2,3-triazoles using the CuAAC reaction and determination of their antioxidant activities

Synthesis of new 1,4-disubstituted 1,2,3-triazoles using the CuAAC reaction and determination of their antioxidant activities

Abstract This study describes the synthesis and antioxidant activity of new 1,4-disubstituted 1,2,3-triazoles. These compounds were generated semi-synthetically using the Cu(I)-catalysed azide-alkyne cycloaddition (CuAAC) reaction between ethyl 2-azidoacetate and terminal acetylenes derived from the...

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Bibliographic Details
Main Authors: JOSEFA A. DA CUNHA LIMA, JADSON DE FARIAS SILVA, COSME S. SANTOS, RODRIGO R.A. CAIANA, MARCÍLIO M. DE MORAES, CLAUDIO A.G. DA CÂMARA, JULIANO C.R. FREITAS
Format: Article
Language:English
Published: Academia Brasileira de Ciências 2021-06-01
Series:Anais da Academia Brasileira de Ciências
Subjects:
Antioxidant activity
Free radicals
1,2,3-Triazole
CuAAC Reaction
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652021000500603&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652021000500603&tlng=en

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