Toxoplasma infection in male mice alters dopamine-sensitive behaviors and host gene expression patterns associated with neuropsychiatric disease.

Toxoplasma infection in male mice alters dopamine-sensitive behaviors and host gene expression patterns associated with neuropsychiatric disease.

During chronic infection, the single celled parasite, Toxoplasma gondii, can migrate to the brain where it has been associated with altered dopamine function and the capacity to modulate host behavior, increasing risk of neurocognitive disorders. Here we explore alterations in dopamine-related behav...

Full description

Bibliographic Details
Main Authors: Graham L Cromar, Jonathan R Epp, Ana Popovic, Yusing Gu, Violet Ha, Brandon J Walters, James St Pierre, Xuejian Xiong, John G Howland, Sheena A Josselyn, Paul W Frankland, John Parkinson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-07-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0010600

Internet

https://doi.org/10.1371/journal.pntd.0010600

Similar Items