A feedback regulatory model for RifQ-mediated repression of rifamycin export in Amycolatopsis mediterranei
Abstract Background Due to the important role of rifamycin in curing tuberculosis infection, the study on rifamycin has never been stopped. Although RifZ, which locates within the rifamycin biosynthetic cluster, has recently been characterized as a pathway-specific regulator for rifamycin biosynthes...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-01-01
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Series: | Microbial Cell Factories |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12934-018-0863-5 |