A feedback regulatory model for RifQ-mediated repression of rifamycin export in Amycolatopsis mediterranei

A feedback regulatory model for RifQ-mediated repression of rifamycin export in Amycolatopsis mediterranei

Abstract Background Due to the important role of rifamycin in curing tuberculosis infection, the study on rifamycin has never been stopped. Although RifZ, which locates within the rifamycin biosynthetic cluster, has recently been characterized as a pathway-specific regulator for rifamycin biosynthes...

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Bibliographic Details
Main Authors: Chao Lei, Jingzhi Wang, Yuanyuan Liu, Xinqiang Liu, Guoping Zhao, Jin Wang
Format: Article
Language:English
Published: BMC 2018-01-01
Series:Microbial Cell Factories
Subjects:
Rifamycin
Amycolatopsis mediterranei
rifQ
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Feedback regulation
Online Access:http://link.springer.com/article/10.1186/s12934-018-0863-5

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