<i>TIAM2</i> Contributes to Osimertinib Resistance, Cell Motility, and Tumor-Associated Macrophage M2-like Polarization in Lung Adenocarcinoma

<i>TIAM2</i> Contributes to Osimertinib Resistance, Cell Motility, and Tumor-Associated Macrophage M2-like Polarization in Lung Adenocarcinoma

<b>Background:</b> Osimertinib-based therapy effectively improves the prognosis of lung adenocarcinoma (LUAD) patients with epidermal growth factor receptor mutations. However, patients will have cancer progression after approximately one year due to the occurrence of drug resistance. Ex...

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Bibliographic Details
Main Authors: Lu Liang, Hua He, Shiyao Jiang, Yueying Liu, Jingjing Huang, Xiaoyan Sun, Yi Li, Yiqun Jiang, Li Cong
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:International Journal of Molecular Sciences
Subjects:
lung adenocarcinoma
lipid metabolism
osimertinib resistance index
M2-like tumor-associated macrophage
<i>TIAM2</i>
Online Access:https://www.mdpi.com/1422-0067/23/18/10415

Internet

https://www.mdpi.com/1422-0067/23/18/10415

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