Caspase-11, a specific sensor for intracellular lipopolysaccharide recognition, mediates the non-canonical inflammatory pathway of pyroptosis

Caspase-11, a specific sensor for intracellular lipopolysaccharide recognition, mediates the non-canonical inflammatory pathway of pyroptosis

Abstract Pyroptosis, a type of programmed cell death that along with inflammation, is mainly regulated by two main pathways, cysteinyl aspartate specific proteinase (caspase)-1-induced canonical inflammatory pathway and caspase-11-induced non-canonical inflammatory pathway. The non-canonical inflamm...

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Bibliographic Details
Main Authors: Xiaoli Huang, Yang Feng, Guanqing Xiong, Shona Whyte, Jing Duan, Yucen Yang, Kaiyu Wang, Shiyong Yang, Yi Geng, Yangping Ou, Defang Chen
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Cell & Bioscience
Subjects:
Pyroptosis
Non-canonical inflammatory pathway
Caspase-1
Caspase-11
Online Access:http://link.springer.com/article/10.1186/s13578-019-0292-0

Internet

http://link.springer.com/article/10.1186/s13578-019-0292-0

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