Iron-Chelation Treatment by Novel Thiosemicarbazone Targets Major Signaling Pathways in Neuroblastoma

Despite constant advances in the field of pediatric oncology, the survival rate of high-risk neuroblastoma patients remains poor. The molecular and genetic features of neuroblastoma, such as <i>MYCN</i> amplification and stemness status, have established themselves not only as potent pro...

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Bibliographic Details
Main Authors: Peter Macsek, Jan Skoda, Maria Krchniakova, Jakub Neradil, Renata Veselska
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/23/1/376