Single-cell transcriptomic characterization reveals the landscape of airway remodeling and inflammation in a cynomolgus monkey model of asthma

Single-cell transcriptomic characterization reveals the landscape of airway remodeling and inflammation in a cynomolgus monkey model of asthma

Monkey disease models, which are comparable to humans in terms of genetic, anatomical, and physiological characteristics, are important for understanding disease mechanisms and evaluating the efficiency of biological treatments. Here, we established an A.suum-induced model of asthma in cynomolgus mo...

Full description

Bibliographic Details
Main Authors: Yingshuo Wang, Xinyan Dong, Caizhe Pan, Cihang Zhu, Hantao Qi, Yifan Wang, Hao Wei, Qiangmin Xie, Lei Wu, Huijuan Shen, Shuxian Li, Yicheng Xie
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Immunology
Subjects:
monkey (Macaca fascicularis)
asthma
scRNA-seq
airway remodeling
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1040442/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1040442/full

Similar Items