Quantitative Acetylomics Uncover Acetylation-Mediated Pathway Changes Following Histone Deacetylase Inhibition in Anaplastic Large Cell Lymphoma

Quantitative Acetylomics Uncover Acetylation-Mediated Pathway Changes Following Histone Deacetylase Inhibition in Anaplastic Large Cell Lymphoma

Histone deacetylases (HDACs) target acetylated lysine residues in histone and non-histone proteins. HDACs are implicated in the regulation of genomic stability, cell cycle, cell death and differentiation and thus critically involved in tumorigenesis. Further, HDACs regulate T-cell development and HD...

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Bibliographic Details
Main Authors: Maša Zrimšek, Hana Kuchaříková, Kristina Draganić, Pavlína Dobrovolná, Verena Heiss Spornberger, Lisa Winkelmayer, Melanie R. Hassler, Gabriela Lochmanová, Zbyněk Zdráhal, Gerda Egger
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Cells
Subjects:
histone deacetylases
histone deacetylase inhibitors
SAHA
vorinostat
MS-275
entinostat
Online Access:https://www.mdpi.com/2073-4409/11/15/2380

Internet

https://www.mdpi.com/2073-4409/11/15/2380

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