Spatial transcriptomics deconvolution at single-cell resolution using Redeconve

Abstract Computational deconvolution with single-cell RNA sequencing data as reference is pivotal to interpreting spatial transcriptomics data, but the current methods are limited to cell-type resolution. Here we present Redeconve, an algorithm to deconvolute spatial transcriptomics data at single-c...

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Bibliographic Details
Main Authors: Zixiang Zhou, Yunshan Zhong, Zemin Zhang, Xianwen Ren
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-43600-9