Necrosulfonamide Alleviates Acute Brain Injury of Intracerebral Hemorrhage via Inhibiting Inflammation and Necroptosis

Necrosulfonamide Alleviates Acute Brain Injury of Intracerebral Hemorrhage via Inhibiting Inflammation and Necroptosis

ObjectiveIntracerebral hemorrhage (ICH) is the most lethal subtype of stroke, without effective treatment. Necrosulfonamide (NSA), a specific inhibitor for mixed lineage kinase domain-like protein, has been reported to exert neuroprotective effects in neurological diseases by ameliorating neuroinfla...

Full description

Bibliographic Details
Main Authors: Xiangyu Zhang, Yan Zhang, Fei Wang, Yang Liu, V. Wee Yong, Mengzhou Xue
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Molecular Neuroscience
Subjects:
intracerebral hemorrhage
necrosulfonamide
mixed lineage kinase domain-like protein
necroptosis
neuroinflammation
blood-brain barrier
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2022.916249/full

Internet

https://www.frontiersin.org/articles/10.3389/fnmol.2022.916249/full

Similar Items