Molecular mechanisms of mTOR-mediated cisplatin response in tumor cells

Cisplatin (CDDP) is one of the main chemotherapeutic drugs that is widely used in many cancers. However, CDDP resistance is a frequent therapeutic challenge that reduces prognosis in cancer patients. Since, CDDP has noticeable side effects in normal tissues and organs, it is necessary to assess the...

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Bibliographic Details
Main Authors: Amirhosein Maharati, Yasamin Rajabloo, Meysam Moghbeli
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024175147